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Sarms LGD-4033
Other Name:Ligandrol
Purity:99% HPLC
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Product Name: LGD-4033(Ligandrol)
CAS: 1165910-22-4
MF:C14H12F6N2O
MW:338.2482992
Appearance: white powder
Purity: 99.% min
Package: 10g/bag or as customers’request.
Test Method: HPLC
Bodybuilder knows that all testosterone replacement products, testosterone esters, etc. must have a PCT(Post Cycle Therapy) after a Cycle of use.
This is because testosterone is a naturally secreted substance in the body. If exogenous supplementation is used, the body will think that the testosterone level in the body is enough and actively reduce the natural secretion of testosterone. When exogenous supplementation is stopped, the body will have low testosterone level, resulting in a series of symptoms of low testosterone.
For bodybuilders, testosterone supplementation can increase muscle mass and strength, which is the original purpose for many people to start bodybuilding, so bodybuilders using testosterone supplements will be forced to choose a PCT after a normal cycle.
At the same time, another group was trying to develop a class of products that had less impact on their own testosterone levels, and then succeeded in developing selective androgen receptor modulator (SARM).
SARMs has tissue selective activity. They express anabolism in bone and muscle tissue and are highly selective and minimally selective in other tissues and organs. Without causing androgen side effects such as acne and prostate enlargement, SARMs became the bodybuilder’s first choice once developed.
The tissue selective activity of SARMs enables some SARMs to eliminate PCT altogether, such as SR9009,MK677 and GW501516.
Does SARMs LGD4033 needs PCT?
It depends on the dosage.
A dose-dependent increase in muscle mass was observed over 21 days in 76 adult men who received gradually increased doses of LGD4033 0.1mg,0.3mg and 1mg daily. No adverse effects were observed over 21 days. A daily dose of 1mg LGD4033 is enough to increase lean muscle mass by nearly 3 pounds.
According to the survey, in bodybuilder, the dosage used is 5mg-10mg per day.
For beginners, the initial dose is about 2.5g per day.
A large body of data shows that when the dose is less than 5mg per day, there are few significant side effects and no need for post-cycle treatment of PCT.
Some bodybuilders may be physically well tolerated, or may choose a higher dose for a given goal. If a dose of more than 10mg is used daily, between 10 and 20g, it is best to choose PCT at the end of one cycle as appropriate.
Because of extensive metabolism and prolonged exposure to higher doses, there may be a large number of potential metabolites that are susceptible to haptens and secondary immune responses, resulting in certain hepatotoxicity that requires a PCT to repair.
Usually, we choose Nolvadex (tamoxifen) as the PCT after the AAS cycle.
LGD4033 was originally developed to increase anabolism and reduce muscle atrophy associated with catabolism and muscle mass loss. Therefore, LGD4033 is the most suitable SARMs for increasing and maintaining muscle mass, and it is usually possible to achieve this effect using very small amounts.
CAS | 1165910-22-4 |
MF | C14H12F6N2O |
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