Provide Steroids powder Exemestan for bodybuilding cycle

Product Name: Exemestan
Other name: 6-Methylenandrosta-1, 4-diene-3, 17-dione; 10, 13-Dimethyl-6-methylidene-7, 8, 9, 10, 11, 12, 13, 14, 15, 16-decahydrocyclopenta[a]phenanthrene-
MF: C20H24O2
MW: 296.4034
CAS: 107868-30-4
Appearance: White crystalline powder
Purity: 99%
Packing: sample 10g,100g500g,1kg
Storage: Shading, confined preservation

The hormone status of steroid users is very important, and the correct balance between androgen and estrogen plays an important role. Aromatization is a biochemical process that occurs in various tissues, such as breast, adipose tissue, liver and brain; Induced by aromatase, testosterone is converted to estradiol (E2).

In order to prevent the side effects of aromatization (water retention and fat storage), we usually use selective estrogen receptor modulators (SERMs) or more effective aromatase inhibitors (AIS). SERMs (tamoxifen, clomiphene) occupy the estrogen receptor locally, so that the circulating estrogen cannot adhere to the receptor. AI inhibits the production of estrogen by inhibiting the action of aromatase, which converts androgen into estrogen. Two types of AI include suicide steroid inhibitors such as exemestane and non steroidal inhibitors such as anastrozole and letrozole. Exemestane can prevent the rise of estradiol (E2) for a period of time after use, so as to prevent any rebound effect. The drug can almost inhibit the plasma and tissue estrogen level of total estrogen (estradiol-e2) by 85%. Occasionally, synthetic forms of dihydroxytestosterone / DHT (testosterone and drosterone) are also used to enhance the anti estrogen effect.

Nevertheless, estrogen does play an important role in muscle development. Estrogen makes androgen receptors more receptive to anabolic molecules. The study showed that scientists castrated male guinea pigs and then gave them the powerful anabolic steroid 17 alkylated drug methyltrienone (M3). With castration, mice significantly increased estrogen levels and eliminated their androgens. It was observed that the connection between m3 and the receptor was 500% stronger than that before castration. This explains how important estrogen is for the attachment of steroid molecules to the receptor surface.